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PROK1

PROK1,全名為Prokineticin-1,常見別名包括EG-VEGF、PK1、PRK1等。該蛋白主要由內(nèi)分泌腺(如卵巢、睪丸、腎上腺和胎盤)表達,參與血管內(nèi)皮細胞的增殖、遷移和窗孔形成。PROK1蛋白在低氧條件下表達增強,并與血管內(nèi)皮生長因子(VEGF)的表達互補,提示兩者可能協(xié)同作用。近年來,PROK1蛋白在多種疾病中的潛在作用引起關(guān)注,包括心血管疾病、腫瘤和自身免疫性疾病等。針對PROK1蛋白的藥物研發(fā)正在積極進行中,部分創(chuàng)新藥物已進入臨床試驗階段,顯示出良好的治療效果和安全性。例如,一些靶向PROK1蛋白的單克隆抗體藥物被用于治療心血管疾病和腫瘤,而小分子抑制劑則被開發(fā)用于調(diào)節(jié)PROK1蛋白的表達和活性。隨著對PROK1蛋白研究的深入,未來有望開發(fā)出更多針對該蛋白的創(chuàng)新藥物,為相關(guān)疾病的治療提供新的選擇。

熱銷產(chǎn)品

PROK1 Antibody (CSB-PA018746LA01HU)

驗證數(shù)據(jù)

CSB-PA018746LA01HU

IHC image of CSB-PA018746LA01HU diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA018746LA01HU

IHC image of CSB-PA018746LA01HU diluted at 1:200 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human prokineticin 1(PROK1/EG-VEGF) ELISA kit (CSB-E04532h)

驗證數(shù)據(jù)

CSB-E04532h 標準曲線

貨號:CSB-E04532h

規(guī)格:96T/48T

靈敏度:0.078 ng/mL

檢測范圍:0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PROK1 Antibodies

PROK1 for Homo sapiens (Human)

PROK1 Proteins

PROK1 Proteins for Homo sapiens (Human)

PROK1 ELISA Kit

PROK1 ELISA Kit for Homo sapiens (Human)