SIRPB1 Antibody, HRP conjugated

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SIRPB1 Polyclonal antibody
Uniprot No.：

O00241
基因名：

SIRPB1
別名：

SIRPB1 antibody; Signal-regulatory protein beta-1 antibody; SIRP-beta-1 antibody; CD172 antigen-like family member B antibody; CD antigen CD172b antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Signal-regulatory protein beta-1 protein (30-371AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
基因功能參考文獻：
1. SIRPB1 copy-number polymorphism was significantly associated with impulsive-disinhibited personality scores in a dose-dependent manner. PMID: 25039969
2. SIRPbeta1 is a novel IFN-induced microglial receptor that supports clearance of neural debris and Abeta aggregates by stimulating phagocytosis. PMID: 19893026
3. SIRP beta 1 is a disulfide-linked homodimer in leukocytes that regulates neutrophil transepithelial migration PMID: 16081415
4. This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia. PMID: 19034380
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
組織特異性：

Detected in monocytes and dendritic cells.
數據庫鏈接：

HGNC: 15928

OMIM: 603889

UniGene: Hs.664861