GPR137B Antibody

產(chǎn)品詳情

Uniprot No.：

O60478
基因名：

GPR137B
別名：

GPR137B; TM7SF1; Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human GPR137B
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy.; Acts also as a negative regulator of osteoclast activity. Involved in interleukin-4-induced M2 macrophage polarization.
亞細胞定位：

Lysosome membrane; Multi-pass membrane protein.
蛋白家族：

GPR137 family
組織特異性：

Expressed in kidney, heart, brain and placenta.
數(shù)據(jù)庫鏈接：

HGNC: 11862

OMIM: 604658

KEGG: hsa:7107

UniGene: Hs.498160