ASGR2 Antibody

產品詳情

Uniprot No.：

P24721
基因名：

ASGR2
別名：

Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin 2) (HL-2) (mHL-2), Asgr2, Asgr-2
反應種屬：

Ugandan cassava brown streak virus
免疫原：

Recombinant Mouse Asialoglycoprotein receptor 2 (Asgr2), Partial (80-301AA)
免疫原種屬：

Mus musculus (Mouse)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Protein G
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
基因功能參考文獻：
1. ASGP-R2 mediates the clearance of glycoproteins that bear oligosaccharides terminating with Siaalpha2,6Gal and thereby helps maintain the relative concentrations of these glycoproteins in the blood. PMID: 19075021
亞細胞定位：

Membrane; Single-pass type II membrane protein.
組織特異性：

Expressed exclusively in hepatic parenchymal cells.
數據庫鏈接：

KEGG: mmu:11890

STRING: 10090.ENSMUSP00000099632

UniGene: Mm.1357