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Your Good Partner in Biology Research

SLIT2

SLIT2,即分泌型裂隙蛋白2,別名Slit homolog 2 (Drosophila)。它是一種在生物體內廣泛表達的細胞信號轉導分子,屬于Slit家族成員之一,與Robo家族受體相互作用,在神經發育、血管生成、器官及組織發育以及干細胞的增殖調節等過程中發揮作用。SLIT2的作用機制涉及與其經典受體ROBO家族(ROBO1-4)結合,發揮調控細胞遷移及增殖等多項機能 。SLIT2不僅在神經系統發育中起到精確引導軸突生長和神經元遷移的作用,還在腫瘤進程中發揮著作用,如在胰腺導管腺癌的肝轉移中,SLIT2-ROBO1信號軸促進了腫瘤細胞在肝臟的定植和生長。此外,SLIT2的表達水平在不同的癌癥組織中與癌癥進展相關,其在腫瘤微環境中的作用機制是當前研究的熱點之一。

熱銷產品

SLIT2 Antibody (CSB-PA136864)

驗證數據

CSB-PA136864

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA136864(SLIT2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA136864

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA136864(SLIT2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA136864

Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse bladder tissue, Primary antibody: CSB-PA136864(SLIT2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

Human Slit2 ELISA Kit (CSB-E11038h)

驗證數據

CSB-E11038h 標準曲線

貨號:CSB-E11038h

規格:96T/48T

靈敏度:0.195 ng/mL

檢測范圍:0.78 ng/mL-50 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

SLIT2 Antibodies

SLIT2 for Homo sapiens (Human)

SLIT2 Proteins

SLIT2 Proteins for Homo sapiens (Human)

SLIT2 ELISA Kit

SLIT2 ELISA Kit for Homo sapiens (Human)