RRAGA
RRAGA，別名FIP1、RAGA、FIP-1。RRAGA由人類RRAGA基因編碼，該基因位于9號(hào)染色體的p22.1位置。RRAGA是一種G蛋白，具有GTP結(jié)合活性，能夠與RagC/RRAGC或RagD/RRAGD形成異二聚體Rag復(fù)合物，并在細(xì)胞對(duì)氨基酸饑餓的響應(yīng)、自噬的負(fù)調(diào)控以及TORC1信號(hào)的正調(diào)控中發(fā)揮作用。RRAGA通過與GATOR1復(fù)合物共定位，在溶酶體和細(xì)胞核中活躍，參與調(diào)節(jié)mTORC1信號(hào)通路。RRAGA在細(xì)胞生長(zhǎng)、代謝和疾病中扮演重要角色，特別是在氨基酸感應(yīng)和mTORC1信號(hào)傳導(dǎo)中。RRAGA的異常表達(dá)或功能失調(diào)與多種疾病相關(guān)，包括腫瘤和代謝性疾病。
熱銷產(chǎn)品
Recombinant Human Ras-related GTP-binding protein A (RRAGA), partial (CSB-RP034654h)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
RRAGA Antibody (CSB-PA03465A0Rb)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA03465A0Rb at dilution of 1:100
Immunofluorescence staining of A549 cells with CSB-PA03465A0Rb at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
RRAGA Antibodies
RRAGA for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA03465A0Rb | RRAGA Antibody | Human | ELISA, IHC, IF |
| CSB-PA03465C0Rb | RRAGA Antibody, FITC conjugated | Human | |
| CSB-PA03465D0Rb | RRAGA Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA022239 | RRAGA Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA071515 | RRAGA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
RRAGA Proteins
RRAGA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-RP034654h | Recombinant Human Ras-related GTP-binding protein A (RRAGA), partial | E.coli |
| CSB-YP752099HU CSB-EP752099HU CSB-BP752099HU CSB-MP752099HU CSB-EP752099HU-B |
Recombinant Human Ras-related GTP-binding protein A (RRAGA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RRAGA Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP668782BO CSB-EP668782BO CSB-BP668782BO CSB-MP668782BO CSB-EP668782BO-B |
Recombinant Bovine Ras-related GTP-binding protein A (RRAGA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RRAGA Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP733938RA CSB-EP733938RA CSB-BP733938RA CSB-MP733938RA CSB-EP733938RA-B |
Recombinant Rat Ras-related GTP-binding protein A (Rraga) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RRAGA Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP767346MO CSB-EP767346MO CSB-BP767346MO CSB-MP767346MO CSB-EP767346MO-B |
Recombinant Mouse Ras-related GTP-binding protein A (Rraga) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
