MGP
MGP，全稱為基質(zhì)γ-羧基谷氨酸蛋白，是一種維生素K依賴性蛋白，常見(jiàn)別名包括MGLAP、NTI、GIG36等。該蛋白主要存在于骨骼、軟骨、心臟、腎臟和肺等組織中，具有抑制鈣離子在軟組織中異常沉積的作用。MGP蛋白通過(guò)與鈣離子結(jié)合，形成可溶性復(fù)合物，從而阻止礦物質(zhì)在組織內(nèi)的沉積，有助于維持骨骼和血管的健康。研究表明，MGP蛋白的表達(dá)水平與多種疾病相關(guān)，如Keutel綜合征，這是一種罕見(jiàn)的遺傳病，患者會(huì)出現(xiàn)軟骨鈣化、肺動(dòng)脈狹窄和面部發(fā)育不全等癥狀。此外，MGP蛋白也與動(dòng)脈鈣化、骨質(zhì)疏松等疾病的發(fā)生發(fā)展密切相關(guān)。目前，針對(duì)MGP蛋白的藥物研發(fā)尚處于早期階段，但已有研究顯示，通過(guò)調(diào)節(jié)MGP蛋白的表達(dá)或活性，可能為治療這些疾病提供新的策略。
熱銷產(chǎn)品
Recombinant Human Matrix Gla protein (MGP) (CSB-EP013789HUb1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Matrix Gla Protein,MGP ELISA Kit (CSB-E09714h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E09714h
規(guī)格：96T/48T
靈敏度：1.95 pg/mL
檢測(cè)范圍：7.8 pg/mL-500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
MGP Antibodies
MGP for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA013789GA01HU | MGP Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA013789LA01HU | MGP Antibody | Human | ELISA, IHC |
| CSB-PA013789LD01HU | MGP Antibody, Biotin conjugated | Human | ELISA |
MGP Proteins
MGP Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP013789HU CSB-BP013789HU CSB-MP013789HU CSB-EP013789HU-B |
Recombinant Human Matrix Gla protein (MGP) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP013789HU | Recombinant Human Matrix Gla protein (MGP) | E.coli |
| CSB-EP013789HUb1 | Recombinant Human Matrix Gla protein (MGP) | E.coli |
MGP ELISA Kit
MGP ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09714h | Human Matrix Gla Protein,MGP ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 1.95 pg/mL |
| CSB-EC013789HU | Human undercarboxylated matrix Gla protein (ucMGP)ELISA kit | serum, plasma | 0.039 ng/mL |
