ME2
ME2，即NADP依賴(lài)性蘋(píng)果酸酶2，別名NAD-ME、ODS1，源自哺乳動(dòng)物細(xì)胞線粒體，是三羧酸循環(huán)的重要補(bǔ)充酶。它催化蘋(píng)果酸轉(zhuǎn)化為丙酮酸，促進(jìn)NAD(P)H生成，維持細(xì)胞代謝平衡。在生物學(xué)上，ME2不僅調(diào)控細(xì)胞能量和還原當(dāng)量供應(yīng)，還通過(guò)影響fumarate水平調(diào)節(jié)CD8+ T細(xì)胞功能和抗腫瘤免疫，展現(xiàn)其在免疫調(diào)節(jié)中的關(guān)鍵作用。此外，ME2的異常表達(dá)與多種腫瘤代謝途徑相關(guān)，是腫瘤代謝研究的熱點(diǎn)之一。ME2在細(xì)胞代謝、免疫調(diào)節(jié)及腫瘤生物學(xué)中均占據(jù)重要地位。
熱銷(xiāo)產(chǎn)品
Recombinant Human NAD-dependent malic enzyme, mitochondrial protein (ME2) (CSB-AP000101HU)
驗(yàn)證數(shù)據(jù)
ME2 Antibody (CSB-PA013633HA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA013633HA01HU at dilution of 1:100
ME2 Antibodies
ME2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA010151 | ME2 Antibody | Human | WB, IHC, ELISA |
| CSB-PA013633HA01HU | ME2 Antibody | Human | ELISA, IHC |
| CSB-PA013633HB01HU | ME2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA013633HC01HU | ME2 Antibody, FITC conjugated | Human | |
| CSB-PA013633HD01HU | ME2 Antibody, Biotin conjugated | Human | ELISA |
ME2 Proteins
ME2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP013633HU CSB-EP013633HU CSB-BP013633HU CSB-MP013633HU CSB-EP013633HU-B |
Recombinant Human NAD-dependent malic enzyme, mitochondrial (ME2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP000101HU | Recombinant Human NAD-dependent malic enzyme, mitochondrial protein (ME2) | E.Coli |
