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Your Good Partner in Biology Research

DKK2

DKK2,全稱為Dickkopf-related protein 2,是一種分泌性蛋白,在多種組織中表達(dá)。該蛋白屬于Dickkopf家族,與Wnt信號(hào)通路密切相關(guān)。DKK2蛋白通過(guò)抑制Wnt信號(hào)通路的傳導(dǎo),參與多種生理和病理過(guò)程,如細(xì)胞增殖、分化、凋亡和組織發(fā)育等。研究表明,DKK2蛋白的表達(dá)增強(qiáng)與多種癌癥的發(fā)生發(fā)展密切相關(guān),如結(jié)直腸癌、膀胱癌、肝癌等。此外,DKK2蛋白也與一些骨骼疾病相關(guān)。基于DKK2蛋白的作用機(jī)制,研究人員正在開(kāi)發(fā)針對(duì)DKK2蛋白的藥物,用于癌癥和骨骼疾病的防治。

熱銷(xiāo)產(chǎn)品

Recombinant Human Dickkopf-related protein 2 (DKK2) (CSB-EP866207HU)

驗(yàn)證數(shù)據(jù)

CSB-EP866207HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

DKK2 Antibody (CSB-PA08279A0Rb)

驗(yàn)證數(shù)據(jù)

CSB-PA08279A0Rb

Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: DKK2 antibody at 3.9μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29 kDa
Observed band size: 32 kDa

CSB-PA08279A0Rb

IHC image of CSB-PA08279A0Rb diluted at 1:500 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA08279A0Rb

IHC image of CSB-PA08279A0Rb diluted at 1:500 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Dickkopf-related protein 2(DKK2) ELISA kit (CSB-EL006921HU)

驗(yàn)證數(shù)據(jù)

CSB-EL006921HU 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-EL006921HU

規(guī)格:96T/48T

靈敏度:0.078 ng/mL

檢測(cè)范圍:0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

DKK2 Antibodies

DKK2 for Homo sapiens (Human)

DKK2 Proteins

DKK2 Proteins for Mus musculus (Mouse)

DKK2 Proteins for Homo sapiens (Human)

DKK2 ELISA Kit

DKK2 ELISA Kit for Homo sapiens (Human)