CYP11A1
CYP11A1，即細(xì)胞色素P450家族11亞家族A1，別名P450scc、CYPXIA1、CYPXI等。它是一種由CYP11A1基因編碼的酶，屬于細(xì)胞色素P450超家族成員，在腎上腺皮質(zhì)細(xì)胞中表達(dá)。CYP11A1的作用機(jī)制涉及催化膽固醇側(cè)鏈的裂解，是合成類(lèi)固醇激素的第一步，將膽固醇轉(zhuǎn)化為孕烯醇酮。CYP11A1參與了腎上腺皮質(zhì)激素的生物合成過(guò)程，包括皮質(zhì)醇、醛固酮和性激素等。CYP11A1的活性對(duì)于維持正常的生理功能和應(yīng)對(duì)壓力至關(guān)重要。此外，CYP11A1的功能異常與某些疾病有關(guān)，如腎上腺增生、腎上腺皮質(zhì)癌等。
熱銷(xiāo)產(chǎn)品
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CYP11A1 Antibody (CSB-PA006389LA01HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: CYP11A1 antibody at 2µg/ml + Rat adrenal gland tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 61, 43 kDa
Observed band size: 61 kDa
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA006389LA01HU at dilution of 1:100
CYP11A1 Antibodies
CYP11A1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA006389GA01HU | CYP11A1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA006389LA01HU | CYP11A1 Antibody | Human, Rat | ELISA, WB, IHC |
| CSB-PA914189 | CYP11A1 Antibody | Human | ELISA,WB |
| CSB-PA005154 | CYP11A1 Antibody | Human | WB, ELISA |
| CSB-PA007585 | CYP11A1 Antibody | Human | WB, ELISA |
| CSB-PA048582 | CYP11A1 Antibody | Human | ELISA,WB |
| CSB-PA898841 | CYP11A1 Antibody | Human | ELISA,IHC |
CYP11A1 Proteins
CYP11A1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP006389HU CSB-BP006389HU CSB-MP006389HU |
Recombinant Human Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1) | Yeast Baculovirus Mammalian cell |
| CSB-EP006389HU | Recombinant Human Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1) | E.coli |
| CSB-EP006389HU-B | Recombinant Human Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1),Biotinylated | E.coli |
