CLEC6A
CLEC6A，全稱為C型凝集素結構域家族6成員A，常見別名包括Dectin-2、C-type lectin domain family 6 member A、CLECSF10、CLEC6A、CLEC4N等。該蛋白屬于C型凝集素受體家族，主要表達于免疫細胞表面，如巨噬細胞、樹突狀細胞和中性粒細胞等。CLEC6A蛋白能夠識別病原體表面的糖類分子，如β-葡聚糖，從而在先天免疫中發揮重要作用。它通過識別真菌細胞壁成分激活下游信號通路，觸發炎癥因子釋放和吞噬作用，幫助機體防御真菌感染。CLEC6A蛋白的表達異常可能與慢性黏膜皮膚念珠菌病等真菌易感性疾病相關，而過度激活則可能與自身免疫疾病或炎癥性疾病相關。目前，針對CLEC6A蛋白的藥物研發主要集中在免疫調節和抗感染領域，例如開發能夠特異性結合CLEC6A蛋白的抗體或小分子化合物，以調節免疫反應或增強機體抗感染能力。
熱銷產品
CLEC4A Antibody (CSB-PA412681)
驗證數據
Western Blot analysis of HEPG2 cells using CLECSF6 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
CLEC6A Antibodies
CLEC6A for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA181586 | CLEC4A Antibody | Human,Mouse | ELISA,WB |
| CSB-PA016840 | CLEC4A Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA412681 | CLEC4A Antibody | Human | WB,ELISA |
CLEC6A Proteins
CLEC6A Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP891558HU CSB-EP891558HU CSB-BP891558HU CSB-MP891558HU CSB-EP891558HU-B |
Recombinant Human C-type lectin domain family 4 member A (CLEC4A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
