CBLB

CBLB，即Casitas B淋巴瘤原癌基因B，別名Cbl-b、Nbla00127、RNF56。它來源于人類基因組，具體由CBLB基因編碼。CBLB是一種RING型E3泛素連接酶，屬于Cbl家族成員，在調(diào)節(jié)T細(xì)胞功能方面發(fā)揮核心作用。其作用機(jī)制是通過促進(jìn)特定底物的泛素化，進(jìn)而調(diào)控這些底物的降解或功能，從而負(fù)向調(diào)節(jié)免疫功能。在生物學(xué)上，CBLB的活性抑制可以增強(qiáng)抗腫瘤免疫效應(yīng)，因?yàn)樗軌驕p少腫瘤細(xì)胞通過高表達(dá)CBLB實(shí)現(xiàn)的免疫逃逸。因此，CBLB在癌癥免疫治療中具有重要的研究價值和應(yīng)用前景。

熱銷產(chǎn)品

Recombinant Human E3 ubiquitin-protein ligase CBL-B (CBLB), partial

CSB-YP623789HU

來源：Yeast

CSB-EP623789HU

來源：E.coli

CSB-BP623789HU

來源：Baculovirus

CSB-MP623789HU

來源：Mammalian cell

CSB-EP623789HU-B

來源：In Vivo Biotinylation in E.coli

CBLB Antibody

CBLB Protein

CBLB Antibodies

CBLB for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA004579GA01HU	CBLB Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IP

CBLB Proteins

CBLB Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP623789HU CSB-EP623789HU CSB-BP623789HU CSB-MP623789HU CSB-EP623789HU-B	Recombinant Human E3 ubiquitin-protein ligase CBL-B (CBLB), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CBLB Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP667545MO CSB-EP667545MO CSB-BP667545MO CSB-MP667545MO CSB-EP667545MO-B	Recombinant Mouse E3 ubiquitin-protein ligase CBL-B (Cblb), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CBLB Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP715671XBF CSB-EP715671XBF CSB-BP715671XBF CSB-MP715671XBF CSB-EP715671XBF-B	Recombinant Xenopus tropicalis E3 ubiquitin-protein ligase CBL-B (cblb), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CBLB Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP814329RA CSB-EP814329RA CSB-BP814329RA CSB-MP814329RA CSB-EP814329RA-B	Recombinant Rat E3 ubiquitin-protein ligase CBL-B (Cblb), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli