STBD1 Antibody

說(shuō)明書(shū)

產(chǎn)品詳情

Uniprot No.：

O95210
基因名：

STBD1
別名：

STBD1; GENX-3414; Starch-binding domain-containing protein 1; Genethonin-1; Glycophagy cargo receptor STBD1
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse
免疫原：

Human STBD1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a cargo receptor for glycogen. Delivers its cargo to an autophagic pathway called glycophagy, resulting in the transport of glycogen to lysosomes.
基因功能參考文獻(xiàn)：
1. results demonstrate that Stbd1 plays a dominant role in glycogen transport to lysosomes in liver and that the N-terminal transmembrane region and the C-terminal CBM20 domain are critical for this function. PMID: 27358407
2. Atg8 interacting motif (AIM) in Stbd1 is necessary for GABARAPL1 binding. PMID: 21893048
亞細(xì)胞定位：

Preautophagosomal structure membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Cell membrane, sarcolemma, T-tubule.
組織特異性：

Expressed at high level in skeletal and cardiac muscles. Moderately expressed in liver and placenta. No expression is found in pancreas, kidney or lung. Present in skeletal muscle, heart and placenta (at protein level).
數(shù)據(jù)庫(kù)鏈接：

HGNC: 24854

OMIM: 607406

KEGG: hsa:8987

STRING: 9606.ENSP00000237642

UniGene: Hs.109590