日韩在线视频不卡-日一区二区三区-天堂国产+人+综合+亚洲欧美-精品国产一区二区三区久久狼-国产成人无码18禁午夜福利网址-国产在线拍偷自揄拍精品-九色91丨porny丨丝袜-久久天天躁狠狠躁夜夜av-99蜜桃臀久久久欧美精品-成人一区二区视频-狠狠操人人干-40岁干柴烈火少妇高潮不断-国产福利不卡-伊人98-丰满多毛的陰户视频-日韩一二三四五区-国产专区一线二线三线码-好男人社区影院www-国产精品2019-欧美三级一区

Your Good Partner in Biology Research

Recombinant Macaca mulatta Semaphorin-4D isoform 1 (SEMA4D), partial (Active)

In Stock Promotion
  • 中文名稱:
    獼猴SEMA4D重組蛋白
  • 品名簡稱:
    Recombinant Rhesus macaque SEMA4D protein, partial (Active)
  • 貨號:
    CSB-MP3947MOW
  • 說明書:
  • 規格:
    ¥816
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Activity
      Measured by its binding ability in a functional ELISA. Immobilized Rhesus macaque SEMA4D at 2 μg/mL can bind Anti-SEMA4D recombinant antibody (CSB-RA835707A1HU), the EC50 is 1.943-2.724 ng/mL. Biological Activity Assay
  • 促銷:
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 內毒素:
    Less than 1.0 EU/ug as determined by LAL method.
  • 生物活性:
    Measured by its binding ability in a functional ELISA. Immobilized Rhesus macaque SEMA4D at 2 μg/mL can bind Anti-SEMA4D recombinant antibody (CSB-RA835707A1HU), the EC50 is 1.943-2.724 ng/mL.
  • 基因名:
  • Uniprot No.:
  • 別名:
    (EGK_07847)
  • 分子結構:
  • 種屬:
    Macaca mulatta (Rhesus macaque)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    81.9 kDa
  • 表達區域:
    24-734aa
  • 氨基酸序列
    FAPIPRITWEHREVRLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSSLVFNVLRDVFVLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSIAEEVFSHGKYMQSATVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSSKKGRRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALYQTESPSRGLVQEMSGDASVCPDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPKYGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSVVQTEGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPVPTSTSCEPKIVINTVPQLHSEKTMYLKSSDNR
  • 蛋白標簽:
    C-terminal 10xHis-tagged
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    SEMA4D Macaca mulatta recombinant protein produced in mammalian cells is a single polypeptide containing the amino acid sequence that encodes Phe24 - Arg734 of the Macaca mulatta SEMA4D and having a molecular weight of approximately 90 kDa on SDS-PAGE. This recombinant SEMA4D protein is expressed a 10xHis-tag at C-Terminus. Its purity is greater than 95% measured by SDS-PAGE. It contains low endotoxin, less than 1.0 EU/ug determined by the LAL method. In the functional ELISA, this SEMA4D protein can bind to the anti-SEMA4D recombinant antibody, with EC50 of 1.943-2.724 ng/mL, confirming it is an active protein.

    SEMA4D, also known as CD100, plays an important role in the immune and nervous systems. It is involved in platelet inactivation, angiogenesis stimulation, and bone formation regulation. SEMA4D expressed on osteoclasts is a coupling factor that suppresses osteoblast differentiation. As a result, inhibiting SEMA4D could be beneficial to bone growth. SEMA4D is also highly expressed in a variety of tumor tissues, including squamous cell carcinoma of the head and neck, prostate cancer, and colon cancer. SEMA4D-Plexin B1 signaling is frequently dysregulated in malignancies, implying that SEMA4D plays a role in cancer progression, invasion, tumor angiogenesis, tumor-associated macrophage modulation, and skeletal metastasis.

  • Datasheet & COA:
    Please contact us to get it.

產品評價