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  4. Rat Interleukin 11,IL-11 ELISA KIT

Rat Interleukin 11,IL-11 ELISA KIT

  • 中文名稱：
    大鼠白介素11(IL-11)酶聯免疫試劑盒
  • 貨號：
    CSB-E07358r
  • 規格：
    96T/48T
  • 價格：
    ￥3200/￥2500
  • 促銷：
  • 其他：

產品詳情

  • 產品描述：
    大鼠白介素11(IL-11)酶聯免疫試劑盒（CSB-E07358r）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的IL11含量。IL11是重要靶點。它是一種細胞因子，參與多種生理和病理過程。在研究機制上，IL11與受體結合激活信號通路，影響細胞的增殖、分化等。當前圍繞它在腫瘤、纖維化疾病等方面的研究較多，有望為相關疾病治療帶來新策略。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL，科研人員可借助該產品探究IL - 11在炎癥性疾病模型、再生醫學研究或藥物干預實驗中的動態變化，為揭示其生物學功能及信號通路機制提供可靠數據支持。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
  • 別名：
    Il11 ELISA Kit; Interleukin-11 ELISA Kit; IL-11 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Rattus norvegicus (Rat)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    15.6 pg/mL-1000 pg/mL
  • 靈敏度：
    3.9 pg/mL
  • 反應時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領域：
    Immunology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of rat IL-11 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　SampleSerum(n=4)
    1:1Average %88
    Range %81-94
    1:2Average %85
    Range %80-90
    1:4Average %92
    Range %86-101
    1:8Average %95
    Range %89-102
  • 回收率：
    The recovery of rat IL-11 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9080-105
    EDTA plasma (n=4)9890-103
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    10002.179 2.116 2.148 2.055
    5001.773 1.704 1.739 1.646
    2501.426 1.313 1.370 1.277
    1251.009 0.959 0.984 0.891
    62.50.537 0.517 0.527 0.434
    31.20.262 0.250 0.256 0.163
    15.60.198 0.186 0.192 0.099
    00.095 0.090 0.093 　
  • 數據處理：
  • 貨期：
    3-5 working days

產品評價

靶點詳情

  • 功能：
    Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling'.
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    IL-6 superfamily
  • 數據庫鏈接：