IL1R2

IL1R2，全稱白細胞介素1受體2型，是一種重要的免疫調(diào)節(jié)蛋白，常見別名為IL-1R2或CD121b。該蛋白主要通過與白細胞介素1α、1β和1受體I型結(jié)合，發(fā)揮阻斷信號傳導(dǎo)的作用，從而抑制炎癥反應(yīng)。IL1R2在多種細胞中表達，包括中性粒細胞、B細胞、單核細胞和巨噬細胞等，參與調(diào)節(jié)免疫應(yīng)答和炎癥反應(yīng)。IL1R2的表達上調(diào)與多種疾病相關(guān)，如腫瘤、自身免疫性疾病和炎癥性疾病等。近年來，IL1R2已成為藥物研發(fā)的重要靶點，已有多種針對IL1R2的抗體藥物進入臨床試驗階段，用于治療腫瘤和自身免疫性疾病。例如，抗IL1R2抗體可阻斷白細胞介素1的作用，從而減輕炎癥反應(yīng)，改善疾病癥狀。此外，IL1R2也被用于腫瘤免疫治療，通過增強抗腫瘤免疫反應(yīng)，提高腫瘤治療效果。IL1R2的研究和應(yīng)用為相關(guān)疾病的治療提供了新的思路和方法。

熱銷產(chǎn)品

Recombinant Human Interleukin-1 receptor type 2 (IL1R2), partial (Active) (CSB-MP011622HU1)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
Measured by its binding ability in a functional ELISA.Immobilized Human IL1B(CSB-MP011614HU) at 5 μg/ml can bind Human IL1R2. The EC₅₀ is 89.65-100.5 ng/mL.

The purity of IL1R2 was greater than 90% as determined by SEC-HPLC

IL1R2 Antibody (CSB-PA011622ESR1HU)

驗證數(shù)據(jù)

Western blot
All lanes: Interleukin-1 receptor type 2 antibody at 3μg/ml + Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 34 kDa
Observed band size: 46 kDa

IL1R2 Antibody

IL1R2 Protein

IL1R2 ELISA Kit

IL1R2 Antibodies

IL1R2 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA011622ESR1HU	IL1R2 Antibody	Human, Mouse	ELISA, WB
CSB-PA005852	IL1R2 Antibody	Human	WB, ELISA
CSB-PA247988	IL1R2 Antibody	Human	ELISA,IHC

IL1R2 Proteins

IL1R2 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011622RA1 CSB-EP011622RA1 CSB-BP011622RA1 CSB-MP011622RA1 CSB-EP011622RA1-B	Recombinant Rat Interleukin-1 receptor type 2 (Il1r2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF011622RA	Recombinant Rat Interleukin-1 receptor type 2 (Il1r2)	in vitro E.coli expression system

IL1R2 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011622HU1 CSB-EP011622HU1 CSB-BP011622HU1 CSB-EP011622HU1-B	Recombinant Human Interleukin-1 receptor type 2 (IL1R2), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-CF011622HU	Recombinant Human Interleukin-1 receptor type 2 (IL1R2)	in vitro E.coli expression system
CSB-MP011622HU1	Recombinant Human Interleukin-1 receptor type 2 (IL1R2), partial (Active)	Mammalian cell

IL1R2 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011622MO1 CSB-EP011622MO1 CSB-BP011622MO1 CSB-MP011622MO1 CSB-EP011622MO1-B	Recombinant Mouse Interleukin-1 receptor type 2 (Il1r2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF011622MO	Recombinant Mouse Interleukin-1 receptor type 2 (Il1r2)	in vitro E.coli expression system

IL1R2 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP644928DSU CSB-EP644928DSU CSB-BP644928DSU CSB-MP644928DSU CSB-EP644928DSU-B	Recombinant Chlorocebus aethiops Interleukin-1 receptor type 2 (IL1R2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli