CUSABIO貨號：CSB-MA177764 ACLY單克隆抗體是針對ATP檸檬酸裂解酶（ACLY）研發(fā)的高特異性科研試劑，該靶點(diǎn)作為細(xì)胞能量代謝關(guān)鍵酶，催化檸檬酸生成乙酰輔酶A，參與脂肪酸和膽固醇生物合成通路，在代謝性疾病與腫瘤發(fā)生機(jī)制研究中具有重要價(jià)值。本產(chǎn)品采用雜交瘤技術(shù)制備，經(jīng)免疫印跡（WB）、酶聯(lián)免疫吸附（ELISA）、免疫細(xì)胞化學(xué)（ICC）及流式細(xì)胞術(shù)（FC）多平臺驗(yàn)證，適用于人源、小鼠、大鼠及豬等多種哺乳動物樣本檢測，具備優(yōu)異的種屬兼容性與實(shí)驗(yàn)穩(wěn)定性。其高親和力特性可精準(zhǔn)識別內(nèi)源性ACLY蛋白，支持代謝重編程研究、腫瘤微環(huán)境分析及心血管疾病模型中脂質(zhì)代謝通路的探索，為分子機(jī)制研究、藥物靶點(diǎn)篩選及信號通路解析提供可靠工具。該抗體特別適用于代謝組學(xué)、癌癥生物學(xué)及細(xì)胞能量調(diào)控領(lǐng)域的科研實(shí)驗(yàn)，配套詳盡的實(shí)驗(yàn)方案與技術(shù)支持，助力科研工作者突破ACLY在脂質(zhì)合成與細(xì)胞增殖中的功能研究瓶頸。

ATP-citrate synthase ATP citrate synthase citrate cleavage enzyme ATP-citrate (pro-S-)-lyase

Mouse

Human,Mouse,Rat,Pig

Recombinant fragment, corresponding to amino acids 734aa-983aa of Human ACLY (C-terminus).

Homo sapiens (Human)

Monoclonal

IgG2a

Antigen Affinity Purified

11H7

It differs from different batches. Please contact us to confirm it.

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

ELISA,WB,ICC,FC

Application	Recommended Dilution
WB	1:500-1:5000
ICC	1:50-1:200

ELISA Protocol
Western Blotting (WB) Protocol
Flow cytometry (FC) Protocol

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.